Ppi dose conversion globalrph
(1) Acts as a pro-drug and must be activated by exposure to acidic pH (< 5).
dexlansoprazole -DEXILANT®
Healing of all grades of erosive esophagitis (EE).
Maintaining healing of EE and relief of heartburn.
Treating heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD).
Healing of EE: 60 mg once daily for up to 8 weeks.
Maintenance of healed EE: 30 mg once daily for up to 6 months.
Symptomatic non-erosive GERD: 30 mg once daily for 4 weeks.
Delayed-Release Capsules: 30 mg and 60 mg.
esomeprazole (Nexium ®)
ESOMEPRAZOLE STRONTIUM delayed-release capsules for oral use
Esomeprazole strontium is a proton pump inhibitor indicated for adults for:
Treatment of gastroesophageal reflux disease (GERD) (1.1)
Risk reduction of NSAID-associated gastric ulcer (1.2)
H. pylori eradication to reduce the risk of duodenal ulcer recurrence (1.3)
Pathological hypersecretory conditions, including Zollinger-Ellison syndrome (1.4)
24.65 mg of esomeprazole strontium (equivalent to 20 mg of esomeprazole)
49.3 mg of esomeprazole strontium (equivalent to 40 mg of esomeprazole)
Lansoprazole (Prevacid ® )
-Short-term treatment: 30 mg orally once daily for up to 8 weeks. Continued treatment for an additional 8 weeks may be considered for recurrence or for patients that do not heal after the first 8 weeks of therapy.
-Maintenance therapy: 15 mg once daily. Alternatively: 30 mg IV once daily for up to 7 days. Patients should be switched to an oral formulation as soon as they can take oral medications.
Omeprazole (Prilosec ® )
Hypersecretory: 60mg once daily.
YOSPRALA⢠(aspirin and omeprazole)
Pantoprazole (Protonix ® )
Short-term treatment erosive esophagitis: 40 mg orally once daily for 8-16 weeks. Alternatively, 40 mg IV once daily infusion for 7-10 days.
Gastroesophageal reflux disease (maintain healing erosive esophagitis): 40 mg orally once daily.
Rabeprazole Sodium (Aciphex ®)
ZEGERID® (omeprazole, sodium bicarbonate)
ZEGERID is a proton pump inhibitor indicated for:
Short-term treatment of active duodenal ulcer
Short-term treatment of active benign gastric ulcer
Treatment of gastroesophageal reflux disease (GERD)
Maintenance of healing of erosive esophagitis
Reduction of risk of upper GI bleeding in critically ill patients
Short-Term Treatment of Active Duodenal Ulcer: 20 mg once daily for 4 weeks (some patients may require an additional 4 weeks of therapy (14.1))
Gastric Ulcer: 40 mg once daily for 4-8 weeks
Gastroesophageal Reflux Disease (GERD)
-Erosive Esophagitis: 20 mg once daily for 4-8 weeks
Reduction of Risk of Upper Gastrointestinal Bleeding in Critically Ill Patients: (40mg oral suspension only) 40 mg initially followed by 40 mg 6-8 hours later and 40 mg daily thereafter for 14 days.
ZEGERID is available as a capsule and as a powder for oral suspension in 20 mg and 40 mg strengths